Original paper
The influence of polygenic risk for bipolar disorder on neural activation assessed using fMRI
Abstract
Genome-wide association studies (GWAS) have demonstrated a significant polygenic contribution to bipolar disorder (BD) where disease risk is determined by the summation of many alleles of small individual magnitude. Modelling polygenic risk scores may be a powerful way of identifying disrupted brain regions whose genetic architecture is related to that of BD. We determined the extent to which common genetic variation underlying risk to BD...
Paper Details
Title
The influence of polygenic risk for bipolar disorder on neural activation assessed using fMRI
Published Date
Jul 3, 2012
Journal
Volume
2
Issue
7
Pages
e130 - e130
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Notes
History