Virology

Biology

Herpesviridae

Asymptomatic

Immunology

Human cytomegalovirus

Viral disease

Antibody

Immune system

Cytomegalovirus

Medicine

Internal medicine

Virus

Journal of Molecular Virology and Immunology

Human cytomegalovirus (CMV), one of the viruses well adapted to the human body, goes into a silent phase after the first infection (primary infection), which is mostly asymptomatic. In the latent phase, the virus presence continues throughout the life of the host, with its ability to form latent infection where viral activity is at very low levels. However, this silence is lost in immunocompromised or immunosuppressed patient groups such as AIDS (Acquired Immune Deficiency Syndrome) patients, solid organ transplant recipients, and patients with hematological malignancies and the reactivated virus may appear with serious diseases. CMV infections are also important due to congenital infections and related complications caused during the fetal period when the immune system is not sufficiently developed. Immune system deficiency is an important risk factor for reactivation of CMV infections, with another perspective CMV, which is one of the largest viruses associated with human infections, is an infectious agent ...

Overview of Human cytomegalovirus (CMV) Infections