Review paper
Rapid Spreading of SARS-CoV-2 Infection and Risk Factors: Epidemiological, Immunological and Virological Aspects
Volume: 1, Issue: 2, Pages: 36 - 50
Published: Sep 22, 2020
Abstract
SARS-CoV-2, the third coronavirus associated with severe respiratory infections in humans, spreads more easily and quickly in the community, with a higher infectiousness rate compared to the other two betacoronavirus species (SARS-CoV and MERS-CoV).The SARS-CoV-2 pandemic, in which the number of cases worldwide has exceeded 30 million, has been the biggest global epidemic of the last century with serious concerns and socio-economic...
Figures & Tables

Figure 1. Spreading characteristics of SARS-CoV-2 infections and preventive meas...
Paper Details
Title
Rapid Spreading of SARS-CoV-2 Infection and Risk Factors: Epidemiological, Immunological and Virological Aspects
Published Date
Sep 22, 2020
Volume
1
Issue
2
Pages
36 - 50
References70
Original paper
# 1Chaolin Huang
18
# 2Yeming Wang(CJFH: China-Japan Friendship Hospital)
28
Last. Bin Cao(CJFH: China-Japan Friendship Hospital)
67
Original paper
# 1Wei‐jie Guan(SKLRD: State Key Laboratory of Respiratory Disease)
37
# 2Zhengyi Ni(Wuhan Pulmonary Hospital)
8
Last. Nanshan Zhong(SKLRD: State Key Laboratory of Respiratory Disease)
72
BackgroundSince December 2019, when coronavirus disease 2019 (Covid-19) emerged in Wuhan city and rapidly spread throughout China, data have been needed on the clinical characteristics of the affected patients.MethodsWe extracted data regarding 1099 patients with laboratory-confirmed Covid-19 from 552 hospitals in 30 provinces, autonomous regions, and municipalities in mainland China through January 29, 2020. The primary composite end point was admission to an intensive care unit (ICU), the use ...
Original paper
# 1Nanshan Chen(Jinyintan Hospital)
8
# 2Min Zhou(SJTU: Shanghai Jiao Tong University)
30
Last. Li Zhang(Jinyintan Hospital)
41
Original paper
# 1Qun Li(HKU: University of Hong Kong)
30
# 2Xuhua Guan(Hubei Provincial Center for Disease Control and Prevention)
14
Last. Zijian Feng(HKU: University of Hong Kong)
43
The initial cases of novel coronavirus (2019-nCoV)-infected pneumonia (NCIP) occurred in Wuhan, Hubei Province, China, in December 2019 and January 2020. We analyzed data on the first 425 confirmed cases in Wuhan to determine the epidemiologic characteristics of NCIP.We collected information on demographic characteristics, exposure history, and illness timelines of laboratory-confirmed cases of NCIP that had been reported by January 22, 2020. We described characteristics of the cases and estimat...
Original paper
# 1Daniel Wrapp(The University of Texas at Austin)
27
# 2Nianshuang Wang(The University of Texas at Austin)
22
Last. Jason S. McLellan(The University of Texas at Austin)
69
The outbreak of a novel coronavirus (2019-nCoV) represents a pandemic threat that has been declared a public health emergency of international concern. The CoV spike (S) glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. To facilitate medical countermeasure development, we determined a 3.5-angstrom-resolution cryo–electron microscopy structure of the 2019-nCoV S trimer in the prefusion conformation. The predominant state of the trimer has one of the three recepto...
Original paper
# 1Stephen A. Lauer(JHU: Johns Hopkins University)
19
# 2Kyra H. Grantz(JHU: Johns Hopkins University)
16
Last. Justin Lessler(JHU: Johns Hopkins University)
63
A novel human coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in China in December 2019. There is limited support for many of its key epidemiologic features, including the incubation period for clinical disease (coronavirus disease 2019 [COVID-19]), which has important implications for surveillance and control activities.
Other
# 1Wen‐Ching Wang(NIVDC: National Institute for Viral Disease Control and Prevention)
40
# 2Yanli Xu(Beijing Ditan Hospital)
14
Last. Wenjie Tan(NIVDC: National Institute for Viral Disease Control and Prevention)
53
This study describes results of PCR and viral RNA testing for SARS-CoV-2 in bronchoalveolar fluid, sputum, feces, blood, and urine specimens from patients with COVID-19 infection in China to identify possible means of non-respiratory transmission.
Other
# 1Lirong Zou(Guangdong Provincial Center for Disease Control and Prevention)
20
# 2Feng Ruan(Zhuhai People's Hospital)
6
Last. Jie Wu(Guangdong Provincial Center for Disease Control and Prevention)
24
SARS-CoV-2 Viral Load in Upper Respiratory Specimens The authors report results of an analysis of nasal and throat swabs from 17 patients in Zhuhai, China, who had received a diagnosis of Covid-19....
Review paper
# 1Yan-Rong Guo(Key Laboratory of Guangdong Province)
1
# 2Qing-Dong Cao(Fifth Affiliated Hospital of Sun Yat-sen University)
1
Last. Yan Yan(Fifth Affiliated Hospital of Sun Yat-sen University)
44
An acute respiratory disease, caused by a novel coronavirus (SARS-CoV-2, previously known as 2019-nCoV), the coronavirus disease 2019 (COVID-19) has spread throughout China and received worldwide attention. On 30 January 2020, World Health Organization (WHO) officially declared the COVID-19 epidemic as a public health emergency of international concern. The emergence of SARS-CoV-2, since the severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002 and Middle East respiratory syndrome cor...
Other
# 1Yan Bai(Henan Provincial People's Hospital)
20
# 2Yao Ling-sheng(Anyang Hospital of Traditional Chinese Medicine)
1
Last. Meiyun Wang(Henan Provincial People's Hospital)
34
This study describes possible transmission of novel coronavirus disease 2019 (COVID-19) from an asymptomatic Wuhan resident to 5 family members in Anyang, a Chinese city in the neighboring province of Hubei.
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