Original paper
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
Abstract
The outbreak of a novel coronavirus (2019-nCoV) represents a pandemic threat that has been declared a public health emergency of international concern. The CoV spike (S) glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. To facilitate medical countermeasure development, we determined a 3.5-angstrom-resolution cryo–electron microscopy structure of the 2019-nCoV S trimer in the prefusion conformation. The...
Paper Details
Title
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
Published Date
Feb 19, 2020
Journal
Volume
367
Issue
6483
Pages
1260 - 1263
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