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The Lancet
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59.10
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Papers 241578
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Published on Jul 1, 2019in The Lancet59.10
K. Reich23
Estimated H-index: 23
(UHH: University of Hamburg),
Melinda Gooderham18
Estimated H-index: 18
(Queen's University)
+ 9 AuthorsDavid A. Williams96
Estimated H-index: 96
(AbbVie)
Summary Background Psoriasis is an autoimmune disease that affects approximately 100 million people worldwide, and is a disease that can be ameliorated by anti-cytokine treatment. We aimed to compare the efficacy and safety of risankizumab with adalimumab in patients with moderate-to-severe plaque psoriasis. Methods IMMvent was a phase 3, randomised, double-blind, active-comparator-controlled trial completed at 66 clinics in 11 countries. Eligible patients were aged 18 years or older with modera...
Published in The Lancet59.10
K. Reich23
Estimated H-index: 23
(UHH: University of Hamburg),
April W. Armstrong38
Estimated H-index: 38
(SC: University of Southern California)
+ -3 AuthorsAndrew Blauvelt53
Estimated H-index: 53
Summary Background Antibodies targeting interleukin (IL)-23 and IL-17A effectively treat moderate-to-severe psoriasis. ECLIPSE is the first comparator study of an IL-23p19 inhibitor, guselkumab, versus an IL-17A inhibitor, secukinumab. The primary objective of this study was to show superiority of clinical response at week 48 for guselkumab versus secukinumab. Methods In this phase 3, multicentre, double-blind, randomised, comparator-controlled trial at 142 outpatient clinical sites in nine coun...
Published in The Lancet59.10
Andreas Rieckmann (SSI: Statens Serum Institut), Christine Stabell Benn38
Estimated H-index: 38
(SSI: Statens Serum Institut)
Published in The Lancet59.10
Geoffrey S. Ginsburg55
Estimated H-index: 55
(Duke University),
R. Ryanne Wu10
Estimated H-index: 10
(Duke University),
Lori A. Orlando19
Estimated H-index: 19
(Duke University)
Summary Family health history (FHH) is the most useful means of assessing risk for common chronic diseases. The odds ratio for risk of developing disease with a positive FHH is frequently greater than 2, and actions can be taken to mitigate risk by adhering to screening guidelines, genetic counselling, genetic risk testing, and other screening methods. Challenges to the routine acquisition of FHH include constraints on provider time to collect data and the difficulty in accessing risk calculator...
Published in The Lancet59.10
Thomas R. Easterling37
Estimated H-index: 37
(UW: University of Washington),
Shuchita Mundle7
Estimated H-index: 7
(Government Medical College, Nagpur)
+ -3 AuthorsBeverly Winikoff43
Estimated H-index: 43
Summary Background Hypertension is the most common medical disorder in pregnancy, complicating one in ten pregnancies. Treatment of severely increased blood pressure is widely recommended to reduce the risk for maternal complications. Regimens for the acute treatment of severe hypertension typically include intravenous medications. Although effective, these drugs require venous access and careful fetal monitoring and might not be feasible in busy or low-resource environments. We therefore aimed ...
Published in The Lancet59.10
Alexander C. Fanaroff6
Estimated H-index: 6
(Duke University),
Robert M. Califf180
Estimated H-index: 180
(Stanford University),
Renato D. Lopes53
Estimated H-index: 53
(Duke University)
Published on Jun 1, 2019in The Lancet59.10
M. James Lozada (VUMC: Vanderbilt University Medical Center), Carolyn F. Weiniger18
Estimated H-index: 18
+ 1 AuthorsJeanette R Bauchat (VUMC: Vanderbilt University Medical Center)
Published on Jun 1, 2019in The Lancet59.10
Guy Brusselle59
Estimated H-index: 59
(EUR: Erasmus University Rotterdam),
F. W. S. Ko12
Estimated H-index: 12
(CUHK: The Chinese University of Hong Kong)
Published in The Lancet59.10
Álvaro González-Cantero2
Estimated H-index: 2
,
Jorge Gonzalez-Cantero2
Estimated H-index: 2
(Hospital General Universitario Gregorio Marañón)
+ -3 AuthorsJorge L. Gonzalez-Calvin9
Estimated H-index: 9
Published in The Lancet59.10
Hanns-Ulrich Marschall46
Estimated H-index: 46
(University of Gothenburg)
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