Original paper

Mutation Enrichment and Transcriptomic Activation Signatures of 419 Molecular Pathways in Cancer

Volume: 12, Issue: 2, Pages: 271 - 271
Published: Jan 22, 2020
Abstract
Carcinogenesis is linked with massive changes in regulation of gene networks. We used high throughput mutation and gene expression data to interrogate involvement of 278 signaling, 72 metabolic, 48 DNA repair and 47 cytoskeleton molecular pathways in cancer. Totally, we analyzed 4910 primary tumor samples with individual cancer RNA sequencing and whole exome sequencing profiles including ~1.3 million DNA mutations and representing thirteen...
Paper Details
Title
Mutation Enrichment and Transcriptomic Activation Signatures of 419 Molecular Pathways in Cancer
Published Date
Jan 22, 2020
Journal
Volume
12
Issue
2
Pages
271 - 271
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