O4-13-03: PLASMA AMYLOID-β MONOMERS AND THE RISK OF CLINICAL CARDIOVASCULAR DISEASE IN THE GENERAL POPULATION: THE ROTTERDAM STUDY

Amyloid-β is a hallmark of Alzheimer's disease (AD), and acts in conjunction with cerebrovascular pathology on the risk of dementia. Although amyloid-β is also abundant in the circulation, its systemic role in various manifestations of vascular disease remains undetermined. Between 1990 and 1993, plasma levels of amyloid-β40 and -β42 (Aβ40 and Aβ42) were measured in a random subset of 1815 participants of the population based Rotterdam Study...