The effect of minocycline on symptoms in schizophrenia: Results from a randomized controlled trial

Studies have hypothesized that immunological abnormalities might contribute to schizophrenia, and basic science studies, as well as several clinical trials suggest that minocycline could be efficacious in ameliorating both positive and negative symptoms of schizophrenia. In this study we examined the effect of minocycline on schizophrenia in a large randomized controlled trial. We performed a 16-week, multi-center, double-blind, randomized,...