Original paper
Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model
Abstract
Adult neurogenesis and Alzheimer's disease Alzheimer's disease (AD) pathology destroys neurons and synapses in the brain, leading to dementia. The brain generates new neurons throughout life in the hippocampus, a process called adult hippocampal neurogenesis (AHN). Choi et al. found that blocking AHN exacerbated cognitive impairment in an AD mouse model (see the Perspective by Spires-Jones and Ritchie). Inducing neurogenesis alone did not...
Paper Details
Title
Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model
Published Date
Sep 7, 2018
Journal
Volume
361
Issue
6406
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Notes
History