Original paper

A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains

Volume: 177, Issue: 1, Pages: 21 - 34
Published: Aug 29, 2017
Abstract
This large multi-center study investigates the relationships between genetic risk for schizophrenia and bipolar disorder, and multi-modal endophenotypes for psychosis. The sample included 4,242 individuals; 1,087 patients with psychosis, 822 unaffected first-degree relatives of patients, and 2,333 controls. Endophenotypes included the P300 event-related potential (N = 515), lateral ventricular volume (N = 798), and the cognitive measures block...
Paper Details
Title
A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains
Published Date
Aug 29, 2017
Volume
177
Issue
1
Pages
21 - 34
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