Original paper

Metaflammasome components in the human brain: a role in dementia with Alzheimer's pathology?

Volume: 27, Issue: 3, Pages: 266 - 275
Published: Jun 8, 2016
Abstract
Epidemiological and genetic studies have identified metabolic disorders and inflammation as risk factors for Alzheimer's disease (AD). Evidence in obesity and type‐2 diabetes suggests a role for a metabolic inflammasome (“metaflammasome”) in mediating chronic inflammation in peripheral organs implicating IKKβ (inhibitor of nuclear factor kappa‐B kinase subunit beta), IRS1 (insulin receptor substrate 1), JNK (c‐jun N‐terminal kinase), and PKR...
Paper Details
Title
Metaflammasome components in the human brain: a role in dementia with Alzheimer's pathology?
Published Date
Jun 8, 2016
Volume
27
Issue
3
Pages
266 - 275
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