Family History of Prostate Cancer in Men Being Followed by Active Surveillance Does Not Increase Risk of Being Diagnosed With High-grade Disease

Objective To assess whether men with a family history of prostate cancer are more likely to fail active surveillance because of recategorization of their tumors on subsequent surveillance biopsies. Methods Men enrolled in an institutional review board–approved active surveillance program were studied, and data on first- and/or second-degree family history of prostate cancer was collected. Analyses were performed to compare the frequency of...