Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining

Published on May 1, 2015in Nature Biotechnology31.86
· DOI :10.1038/nbt.3190
Takeshi Maruyama13
Estimated H-index: 13
(MIT: Massachusetts Institute of Technology),
Stephanie K. Dougan25
Estimated H-index: 25
(MIT: Massachusetts Institute of Technology)
+ 3 AuthorsHidde L. Ploegh115
Estimated H-index: 115
(MIT: Massachusetts Institute of Technology)
The efficiency of homologous recombination-based Cas9 genome editing is increased by inhibiting non-homologous end joining.
Figures & Tables
  • References (32)
  • Citations (460)
#1Priti Singh (Cornell University)H-Index: 2
#2John C. Schimenti (Cornell University)H-Index: 45
Last.Ewelina Bolcun-Filas (Cornell University)H-Index: 11
view all 3 authors...
#1Li Song (Johns Hopkins University)H-Index: 8
#2Liliana Florea (Johns Hopkins University)H-Index: 27
Last.Ben Langmead (Johns Hopkins University)H-Index: 20
view all 3 authors...
#1Clarissa C. Lee (MIT: Massachusetts Institute of Technology)H-Index: 4
#2Elizaveta Freinkman (MIT: Massachusetts Institute of Technology)H-Index: 20
Last.Hidde L. Ploegh (MIT: Massachusetts Institute of Technology)H-Index: 115
view all 4 authors...
#1Hao Yin (MIT: Massachusetts Institute of Technology)H-Index: 22
#2Wen Xue (MIT: Massachusetts Institute of Technology)H-Index: 28
Last.Daniel G. Anderson (MIT: Massachusetts Institute of Technology)H-Index: 86
view all 10 authors...
#1Philippe Frit (University of Toulouse)H-Index: 6
#2Nadia Barboule (University of Toulouse)H-Index: 3
Last.Patrick Calsou (University of Toulouse)H-Index: 10
view all 5 authors...
#1Timothy C. WangH-Index: 55
#2Jenny J. Wei (MIT: Massachusetts Institute of Technology)H-Index: 2
Last.Eric S. Lander (MIT: Massachusetts Institute of Technology)H-Index: 245
view all 4 authors...
#1Yuxuan Wu (CAS: Chinese Academy of Sciences)H-Index: 9
#2Dan Liang (CAS: Chinese Academy of Sciences)H-Index: 7
Last.Jinsong Li (CAS: Chinese Academy of Sciences)H-Index: 27
view all 9 authors...
Cited By460
#1Grégoire Cullot (French Institute of Health and Medical Research)
#2Julian Boutin (French Institute of Health and Medical Research)
Last.Véronique Guyonnet-Duperat (French Institute of Health and Medical Research)H-Index: 12
view all 20 authors...
#1Fatemeh Safari (Shiraz University of Medical Sciences)H-Index: 1
#2Khadijeh Zare (FUM: Ferdowsi University of Mashhad)H-Index: 1
Last.Younes Ghasemi (Shiraz University of Medical Sciences)H-Index: 21
view all 5 authors...
#1Xiu-Ling Zhao (Xida: Guangxi University)H-Index: 1
#2Wei WeiH-Index: 44
Last.Yangqing Lu (Xida: Guangxi University)H-Index: 6
view all 0 authors...
#1Yagiz Aksoy (Macquarie University)H-Index: 1
#2David T. Nguyen (Garvan Institute of Medical Research)H-Index: 1
Last.Daniel Hesselson (UNSW: University of New South Wales)H-Index: 14
view all 7 authors...
#1Rajeswari Jayavaradhan (Cincinnati Children's Hospital Medical Center)H-Index: 2
#2Devin Pillis (Cincinnati Children's Hospital Medical Center)H-Index: 2
Last.Punam Malik (University of Cincinnati Academic Health Center)H-Index: 28
view all 7 authors...
View next paperRNA-Guided Human Genome Engineering via Cas9