Herpesviridae

Gastroenterology

Immunology

Viral disease

Cytomegalovirus

Medicine

Internal medicine

Virus

Urinary system

Journal of Molecular Virology and Immunology

Reactivation of latent viruses such as human cytomegalovirus (CMV), as well as opportunistic infections associated with bacterial and fungal agents, cause serious clinical consequences in patients with hematological malignancies, which are characterized by both immunosuppressive drug use and functional and numerical disorders of immune system cells. In this study, it was aimed to investigate the association between CMV reactivation and the frequency of various simultaneous infections in adult patients with hematological malignancies. All CMV-DNA test results reported in the medical microbiology laboratory between November 2016 and February 2022 were retrospectively reviewed and the study group consisting of 270 adult patients with hematological malignancies was created. CMV-DNA follow-up results and clinical evaluations of these patients were examined and cases with CMV reactivation were determined. In the final stage, the possible association between CMV reactivation and the frequency of other infections ide...

Bacterial, Fungal and Viral Infections in Patients with Hematological Malignancies: Investigation of CMV Reactivation as a Risk Factor