Review paper
Pathogenesis of human cytomegalovirus in the immunocompromised host
Abstract
Human cytomegalovirus (HCMV) is a herpesvirus that infects ~60% of adults in developed countries and more than 90% in developing countries. Usually, it is controlled by a vigorous immune response so that infections are asymptomatic or symptoms are mild. However, if the immune system is compromised, HCMV can replicate to high levels and cause serious end organ disease. Substantial progress is being made in understanding the natural history and...
Figures & Tables

Fig. 1 | Overview of human cytomegalovirus entry into target cells and the estab...

Fig. 5 | Two distinct strategies used to reduce human cytomegalovirus disease in...
Paper Details
Title
Pathogenesis of human cytomegalovirus in the immunocompromised host
Published Date
Jun 24, 2021
Journal
Volume
19
Issue
12
Pages
759 - 773
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