Original paper
Chronic hyperglycemia impairs hippocampal neurogenesis and memory in an Alzheimer’s disease mouse model
Abstract
During aging, lifestyle-related factors shape the brain's response to insults and modulate the progression of neurodegenerative pathologies such as Alzheimer's disease (AD). This is the case for chronic hyperglycemia associated with type 2 diabetes, which reduces the brain's ability to handle the neurodegenerative burden associated with AD. However, the mechanisms behind the effects of chronic hyperglycemia in the context of AD are not fully...
Paper Details
Title
Chronic hyperglycemia impairs hippocampal neurogenesis and memory in an Alzheimer’s disease mouse model
Published Date
Aug 1, 2020
Journal
Volume
92
Pages
98 - 113
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Notes
History