Preserved wake-dependent cortical excitability dynamics predict cognitive fitness beyond age-related brain alterations
Abstract
Age-related cognitive decline arises from alterations in brain structure as well as in sleep-wake regulation. Here, we investigated whether preserved wake-dependent regulation of cortical function could represent a positive factor for cognitive fitness in aging. We quantified cortical excitability dynamics during prolonged wakefulness as a sensitive marker of age-related alteration in sleep-wake regulation in 60 healthy older individuals (50-69...
Paper Details
Title
Preserved wake-dependent cortical excitability dynamics predict cognitive fitness beyond age-related brain alterations
Published Date
Dec 3, 2019
Journal
Volume
2
Issue
1
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