Radiomic Features of the Nigrosome-1 Region of the Substantia Nigra: Using Quantitative Susceptibility Mapping to Assist the Diagnosis of Idiopathic Parkinson's Disease

Introduction: The loss of nigrosome-1 which is also referred to as the swallow tail sign (STS) in T2* weighted iron-sensitive magnetic resonance imaging (MRI) has recently emerged as a new biomarker for idiopathic Parkinson’s disease (IPD). However, consistent recognition of the STS is difficult due to individual variations and different imaging parameters. Radiomics might have the potential to overcome these shortcomings. Therefore, we chose to...