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Frontiers in Aging Neuroscience
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#1Yuki IshimaruH-Index: 7
#2Akihide SuminoH-Index: 1
Last. Sadaaki MaedaH-Index: 14
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#1Shanshan Cao (Anhui Medical University)
#2Jun Zhang (Anhui Medical University)
Last. Wang Ka (Anhui Medical University)H-Index: 26
view all 10 authors...
Introduction: Problems with attention are common in patients with cerebral small vessel disease (CSVD). The normal human brain exhibits functional and structural asymmetry. However, it is unknown whether there is lateralization of attention in patients with CSVD. Objective: This study aims to investigate attention separately in both cerebral hemispheres in patients with CSVD using the computer based Lateralized Attention Network Test (LANT). Methods: The total number of participants included was...
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#1Dayana Hayek (Charité)H-Index: 1
Last. Daria Antonenko (Charité)H-Index: 12
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Age-related deterioration in white and grey matter is linked to cognitive deficits. Reduced microstructure of the fornix, the major efferent pathway of the hippocampus, and volume of the dentate gyrus (DG), may cause age-associated memory decline. However, the linkage between these anatomical determinants and memory formation in healthy aging are poorly understood. In 30 older adults, we acquired diffusion tensor and T1-weighted images for individual deterministic tractography and volume estimat...
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#1Keisuke Kokubun (Kyoto University)H-Index: 2
#2Kiyotaka Nemoto (University of Tsukuba)H-Index: 26
Last. Yoshinori YamakawaH-Index: 2
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As the population ages worldwide, the prevalence of cognitive disorders including mild cognitive impairment (MCI) is increasing. MCI appears in 10% to 20% of adults aged 65 years and older and is generally referred to as an intermediate stage between normal cognitive aging and dementia. To develop timely prevention and early treatment strategies by identifying biological factors, we investigated the relationship between dietary consumption of fish, brain structure, and MCI in cognitively normal ...
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#1Eun Jin Paek (UTHSC: University of Tennessee Health Science Center)H-Index: 2
#2Laura L. MurrayH-Index: 15
Last. Sharlene D. Newman (IU: Indiana University)H-Index: 19
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Currently there are approximately 6 million Americans who are affected by dementia. Verbal fluency tasks have been commonly and frequently utilized to document the disease progression in many forms of dementia. Verb fluency has been found to display substantial potential to detect and monitor the cognitive declines of individuals with dementia who have fronto-striatal involvement. The neural substrates underlying verb fluency task performance, however, have remained unclear so far, especially in...
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#1Lu Liu (ZJU: Zhejiang University)H-Index: 1
#2Lijuan Gu (WHU: Wuhan University)H-Index: 10
Last. Shengmei Zhu (ZJU: Zhejiang University)H-Index: 18
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Stroke remains a leading cause of death, disability, and medical care burden worldwide. However, transformation from laboratory findings toward effective pharmacological interventions for clinical stroke has been unsatisfactory. Novel evidence has been gained on the underlying mechanisms and therapeutic potential related to the transient receptor potential(TRP) channels in several disorders. The TRP superfamily consists of a diverse group of Ca2+ permeable nonselective cation channels. In partic...
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#1Lingyan Liang (Xida: Guangxi University)H-Index: 2
#2Lihua Zhao (Xida: Guangxi University)H-Index: 1
Last. Xiaping Mo (Xida: Guangxi University)H-Index: 1
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Background: Recently, subjective cognitive decline(SCD) has been described as the earliest at-risk state of Alzheimer's disease(AD), and drawn attention of investigators. Studies suggested that SCD-community individuals may be at an earlier state of SCD than SCD-clinic patients, therefore, to investigate the early changes of the brain may provide guidance for intervention and treatment of the disease. We sought to investigate the changes of structure and functional connectivity of the hippocampu...
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#1Focko Lorenz Higgen (UHH: University of Hamburg)H-Index: 1
#2Charlotte Heine (UHH: University of Hamburg)
Last. Christian Gerloff (UHH: University of Hamburg)H-Index: 65
view all 8 authors...
One of the pivotal challenges of aging is to maintain independence in the activities of daily life. In order to adapt to changes in the environment, it is crucial to continuously process and accurately combine simultaneous input from different sensory systems, i.e., crossmodal integration. With aging, performance decreases in multiple cognitive domains. The processing of sensory stimuli constitutes one of the key features of this deterioration. Age-related sensory impairments affect all modaliti...
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