Original paper
Impact of adrenal hormones, reproductive aging, and major depression on memory circuitry decline in early midlife
Abstract
Dehydroepiandrosterone-sulfate (DHEAS) is an adrenal androgen that is, in part, aromatized to estradiol. It continues to be produced after menopause and provides estrogenicity after depletion of ovarian hormones. Estradiol depletion contributes to memory circuitry changes over menopause, including changes in hippocampal (HIPP) and dorsolateral- and ventrolateral-prefrontal cortex (DLPFC; VLPFC) function. Further, major depressive disorder (MDD)...
Paper Details
Title
Impact of adrenal hormones, reproductive aging, and major depression on memory circuitry decline in early midlife
Published Date
Oct 1, 2019
Journal
Volume
1721
Pages
146303 - 146303
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Notes
History