THE IDENTIFICATION OF HETEROGENEOUS GENETIC SUBGROUPS FOR MAJOR DEPRESSIVE DISORDER

Major Depressive Disorder (MDD) is a leading cause of disability worldwide with an estimated heritability of 37%. MDD is clinically heterogeneous and has frequently been shown to be comorbid with a variety of other conditions. Both of these factors have potentially confounded previous attempts to elucidate MDD's genetic architecture. To investigate causal heterogeneity within MDD we sought to identify genetic subgroups associated with other...