European Neuropsychopharmacology
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#1E. Campeny (University of Barcelona)
#2Hugo López-Pelayo (University of Barcelona)H-Index: 7
Last. S. Fernández-Artamendi (LUC: Loyola University Chicago)
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Abstract Cannabis is the third most used psychoactive substance worldwide. The legal status of cannabis is changing in many Western countries, while we have very limited knowledge of the public health impact of cannabis-related harms. There is a need for a summary of the evidence of harms and risks attributed to cannabis use, in order to inform the definition of cannabis risky use. We have conducted a systematic review of systematic reviews, aiming to define cannabis-related harms. We included s...
#1Milou Straathof (UU: Utrecht University)H-Index: 2
#2Erwin L. A. Blezer (UU: Utrecht University)H-Index: 27
Last. Maarten Mennes (Radboud University Nijmegen)H-Index: 35
view all 65 authors...
Abstract Obsessive-compulsive disorder (OCD) is increasingly considered to be a neurodevelopmental disorder. However, despite insights in neural substrates of OCD in adults, less is known about mechanisms underlying compulsivity during brain development in children and adolescents. Therefore, we developed an adolescent rat model of compulsive checking behavior and investigated developmental changes in structural and functional measures in the frontostriatal circuitry. Five-weeks old Sprague Dawl...
#1Martin K. Madsen (UCPH: University of Copenhagen)H-Index: 5
#2Patrick M. Fisher (Copenhagen University Hospital)H-Index: 19
Last. Brice Ozenne (UCPH: University of Copenhagen)H-Index: 7
view all 11 authors...
Abstract A single dose of the serotonin 2A receptor (5-HT2AR) agonist psilocybin can have long-lasting beneficial effects on mood, personality, and potentially on mindfulness, but underlying mechanisms are unknown. Here, we for the first time conduct a study that assesses psilocybin effects on cerebral 5-HT2AR binding with [11C]Cimbi-36 positron emission tomography (PET) imaging and on personality and mindfulness. Ten healthy and psychedelic-naive volunteers underwent PET neuroimaging of 5-HT2AR...
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#1Pamela Prini (University of Insubria)H-Index: 6
#2Erica Zamberletti (University of Insubria)H-Index: 13
Last. Tiziana Rubino (University of Insubria)H-Index: 37
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Abstract A growing body of literature suggests that cannabis intake can induce memory loss in humans and animals. Besides the recreational use, daily cannabis users may also belong to the ever-increasing population of patients who are administered cannabis as a medicine. As such, they also can experience impairments in memory as a negative side effect of their therapy. Comprehension of the neurobiological mechanisms responsible for such detrimental effects would be therefore of paramount relevan...
#1Talise E. Müller (UFSM: Universidade Federal de Santa Maria)H-Index: 5
#2Paola R. Ziani (UFSM: Universidade Federal de Santa Maria)H-Index: 2
Last. Denis Broock Rosemberg (UFSM: Universidade Federal de Santa Maria)H-Index: 26
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Abstract Acute ethanol (EtOH) consumption exerts a biphasic effect on behavior and increases serotonin levels in the brain. However, the molecular mechanisms underlying alcohol-mediated behavioral responses still remain to be fully elucidated. Here, we investigate pharmacologically the involvement of the serotonergic pathway on acute EtOH-induced behavioral changes in zebrafish. We exposed zebrafish to 0.25, 0.5, 1.0% (v/v) EtOH for 1 h and analyzed the effects on aggression, anxiety-like behavi...
#1Kathrin Weidacker (University of Cambridge)H-Index: 1
#2Stephen J. Johnston (Swansea University)H-Index: 18
Last. Simon Dymond (Swansea University)H-Index: 28
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Abstract Discounting larger, delayed rewards for smaller, immediate rewards is a stable psychological trait known to be impaired in gambling disorder (GD). Neuroimaging with non-GD populations indicates involvement of anterior cingulate (ACC) and dorsolateral prefrontal cortex (dlPFC) in delay discounting. However, little is known about the role of intrinsic properties of brain functioning, such as neurotransmitter action, in impaired discounting in GD. Here, we used magnetic resonance spectrosc...
#1H.Z. Rosa (UFSM: Universidade Federal de Santa Maria)H-Index: 3
#2Raquel Cristine Silva Barcelos (UFSM: Universidade Federal de Santa Maria)H-Index: 18
Last. Marilise Escobar Burger (UFSM: Universidade Federal de Santa Maria)H-Index: 24
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Abstract Addiction is a devastating worldwide disorder that requires effective and innovative therapies. Physical exercise could be useful in addiction treatment because it shares a common neural circuit with addictive drugs. Based on this, molecular adaptations consequent to time of exercise in opioid exposed animals were evaluated. Rats were designed as sedentary (SED) or exercised (EXE). This last group was separated to perform three different periods of swimming: short-term (S-EXE), medium-t...
#1Patricia Irizar (University of Liverpool)
#1Patricia Irizar (University of Liverpool)
Last. Valentina Lorenzetti (ACU: Australian Catholic University)H-Index: 21
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Abstract Pathological gambling and cocaine dependence are highly pervasive disorders. Functional neuroimaging evidence implicates aberrant activity of prefrontal striatal pathways in both disorders. It is unclear if the neuroanatomy of these areas is also affected. Participants with pathological gambling (n = 18), cocaine dependence (n = 19) and controls (n = 21) underwent high-resolution structural MRI scan and cognitive assessments. In line with emerging functional neuroimaging findings, we hy...
#1Kazunori TatsumiH-Index: 1
#2Brian Kirkpatrick (University of Nevada, Reno School of Medicine)H-Index: 5
Last. Mark OplerH-Index: 21
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Abstract Negative symptoms are a core feature of schizophrenia and associated with social and occupational impairment. To encourage treatment development and address the limitations of existing rating instruments in this area across culture, the Brief Negative Symptoms Scale (BNSS) was developed. The authors reviewed studies published since the BNSS was published in 2010 that examined the psychometric properties of the instrument in translation and compared for consistency, psychometric performa...
Top fields of study
Clinical psychology