Alterations of DNA methylation profile in proximal jejunum potentially contribute to the beneficial effects of gastric bypass in a diabetic rat model
Volume: 15, Issue: 8, Pages: 1291 - 1298
Published: Aug 1, 2019
Abstract
Background The foregut theory posits that the proximal small intestine plays an important role in the improvement of type 2 diabetes (T2D) after Roux-en-Y gastric bypass (RYGB). Objective To study the possible role of proximal jejunum in the treatment of T2D after RYGB via the analysis of DNA methylation and transcriptome. Setting Laboratory of Shanghai Diabetes Institute, China. Methods Two batches of T2D rats undergoing surgeries (RYGB and a...
Paper Details
Title
Alterations of DNA methylation profile in proximal jejunum potentially contribute to the beneficial effects of gastric bypass in a diabetic rat model
Published Date
Aug 1, 2019
Volume
15
Issue
8
Pages
1291 - 1298
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