S160. Disrupted Salience and Cingulo-Opercular Network Connectivity Underlies Impaired Rapid Task-Learning in Schizophrenia

The salience network (SAN) and cingulo-opercular network (CON) support goal-directed behavior through orienting attention to goal-relevant stimuli and stably maintaining task-context. Both networks are integral in successful cognitive performance, particularly when the task relies on rapid instructed task learning (RITL), the ability to rapidly transform task information into goal-directed behavior without relying on trial-and-error. RITL has...