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Biological Psychiatry
IF
11.50
Papers
19827
Papers 19738
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Published on Jan 1, 2019in Biological Psychiatry 11.50
Hiroshi Nomura13
Estimated H-index: 13
(UTokyo: University of Tokyo),
Hiroto Mizuta1
Estimated H-index: 1
(Kyoto University)
+ 19 AuthorsZohal Baraki1
Estimated H-index: 1
(UTokyo: University of Tokyo)
Abstract Background A method that promotes the retrieval of lost long-term memories has not been well established. Histamine in the central nervous system is implicated in learning and memory, and treatment with antihistamines impairs learning and memory. Because histamine H 3 receptor inverse agonists upregulate histamine release, the inverse agonists may enhance learning and memory. However, whether the inverse agonists promote the retrieval of forgotten long-term memory has not yet been deter...
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Published on Aug 1, 2019in Biological Psychiatry 11.50
Kotaro Mizuta2
Estimated H-index: 2
(Kyoto University),
Takeo Saneyoshi1
Estimated H-index: 1
(Kyoto University)
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Published on Mar 1, 2019in Biological Psychiatry 11.50
Verónica Brito6
Estimated H-index: 6
(University of Barcelona),
Albert Giralt22
Estimated H-index: 22
(University of Barcelona)
+ 7 AuthorsSilvia Ginés23
Estimated H-index: 23
(University of Barcelona)
Abstract Background Depression is the most common psychiatric condition in Huntington’s disease (HD), with rates more than twice those found in the general population. At the present time, there is no established molecular evidence to use as a basis for depression treatment in HD. Indeed, in some patients, classic antidepressant drugs exacerbate chorea or anxiety. Cyclin-dependent kinase 5 (Cdk5) has been involved in processes associated with anxiety and depression. This study evaluated the invo...
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Published on Aug 1, 2018in Biological Psychiatry 11.50
Dongdong Zhao1
Estimated H-index: 1
(Ha Tai: Xiamen University),
Jian Meng1
Estimated H-index: 1
(Ha Tai: Xiamen University)
+ 21 AuthorsHao Sun3
Estimated H-index: 3
(Ha Tai: Xiamen University)
Abstract Background Although synaptic impairment is a prerequisite to cognitive deficiencies in Alzheimer’s disease (AD), mechanisms underlying the dysregulation of essential synaptic scaffolding components and their integrity remain elusive. RPS23RG1 is a newly identified protein implicated in AD. However, the physiological function of RPS23RG1 has yet to be determined. Methods We investigated the role of RPS23RG1 in maintaining synaptic structure and function in cell cultures and in Rps23rg1 k...
2 Citations Source Cite
Published on Apr 1, 2019in Biological Psychiatry 11.50
Bret R. Rutherford18
Estimated H-index: 18
(Columbia University),
Mark Slifstein53
Estimated H-index: 53
(SBU: Stony Brook University)
+ 8 AuthorsEmily Valente
Abstract Background A high-risk subgroup of older patients with depression has slowed processing and gait speeds. This study examined whether carbidopa/levodopa (L-DOPA) monotherapy increased dopamine availability, increased processing/gait speed, and relieved depressive symptoms. Methods Adult outpatients with depression >59 years old underwent baseline [ 11 C]raclopride positron emission tomography followed by open L-DOPA for 3 weeks (1 week each of 150 mg, 300 mg, and 450 mg). Generalized est...
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Published on Jan 1, 2019in Biological Psychiatry 11.50
Julia M. Sheffield9
Estimated H-index: 9
(Vandy: Vanderbilt University),
Baxter P. Rogers26
Estimated H-index: 26
(Vandy: Vanderbilt University)
+ 2 AuthorsNeil D. Woodward25
Estimated H-index: 25
(Vandy: Vanderbilt University)
Abstract Background Across networks, connectivity within the frontoparietal network (FPN) and cingulo-opercular network (CON) exhibits reductions earliest during healthy aging, contributing to cognitive impairment. Individuals with psychotic disorders demonstrate evidence of accelerated aging across multiple biological systems. By leveraging a large sample of patients with psychosis from early to chronic illness stages, this study sought to determine whether the CON and FPN exhibit evidence of a...
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