von Willebrand factor in experimental malaria‐associated acute respiratory distress syndrome

Malaria-associated acute respiratory distress syndrome (MA-ARDS) is a lethal complication of severe malaria, characterized by marked pulmonary inflammation. Patient studies have suggested a link between von Willebrand factor (VWF) and malaria severity.To investigate the role of VWF in the pathogenesis of experimental MA-ARDS.Plasmodium berghei NK65-E (PbNK65) parasites were injected in Vwf+/+ and Vwf-/- mice. Pathological parameters were...