Clinical utility of genetic diagnosis for sporadic and hereditary medullary thyroid carcinoma

Volume: 80, Issue: 3, Pages: 187 - 190
Published: Jun 1, 2019
Abstract
Medullary thyroid cancer (MTC) is a rare thyroid tumor whose prevalence is 3–5% among all thyroid tumors. The pathogenesis of MTC is mainly related to germline or somatic RET activating point mutations that are causative of hereditary and sporadic cases, respectively. Hereditary MTC can occur as multiple endocrine neoplasia type 2A (MEN 2A), type 2B (MEN 2B) and familial MTC (FMTC) that differ for the association with other endocrine neoplasia....
Paper Details
Title
Clinical utility of genetic diagnosis for sporadic and hereditary medullary thyroid carcinoma
Published Date
Jun 1, 2019
Volume
80
Issue
3
Pages
187 - 190
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