Original paper
Oncogenic and osteolytic functions of histone demethylase NO66 in castration-resistant prostate cancer
Abstract
Epigenetic changes that cause dysregulated gene expression during progression of androgen-independent prostate cancer (PCa) and metastatic skeletal lesions remain elusive. Here, we explored the role of histone demethylase NO66 in the pathogenesis of PCa and bone metastasis-related skeletal lesions. Tissue and cDNA microarrays of PCa were analyzed for NO66 mRNA and protein levels. We examined the effects of gain and loss of NO66 function on cell...
Paper Details
Title
Oncogenic and osteolytic functions of histone demethylase NO66 in castration-resistant prostate cancer
Published Date
Mar 11, 2019
Journal
Volume
38
Issue
25
Pages
5038 - 5049
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Notes
History