Original paper
TBA225, a fusion toxoid vaccine for protection and broad neutralization of staphylococcal superantigens
Abstract
Superantigens (SAgs) play a major role in the pathogenesis of Staphylococcus aureus and are associated with several diseases, including food poisoning, bacterial arthritis, and toxic shock syndrome. Monoclonal antibodies to these SAgs, primarily TSST-1, SEB and SEA have been shown to provide protection in animal studies and to reduce clinical severity in bacteremic patients. Here we quantify the pre-existing antibodies against SAgs in many human...
Paper Details
Title
TBA225, a fusion toxoid vaccine for protection and broad neutralization of staphylococcal superantigens
Published Date
Mar 1, 2019
Journal
Volume
9
Issue
1
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Notes
History