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Scientific Reports
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4.01
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90458
Papers 90472
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Published on Mar 26, 2019in Scientific Reports 4.01
Wei-Jie Wang5
Estimated H-index: 5
,
Wenqi Peng4
Estimated H-index: 4
+ 4 AuthorsFei Dong2
Estimated H-index: 2
The need for operational models describing the friction factor f in streams remains undisputed given its utility across a plethora of hydrological and hydraulic applications concerned with shallow inertial flows. For small-scale roughness elements uniformly covering the wetted parameter of a wide channel, the Darcy-Weisbach f = 8(u*/Ub)2 is widely used at very high Reynolds numbers, where u* is friction velocity related to the surface kinematic stress, Ub = Q/A is bulk velocity, Q is flow rate, ...
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Published on Mar 21, 2019in Scientific Reports 4.01
Yongtao Liu1
Estimated H-index: 1
(BNU: Beijing Normal University),
Youzhu Wang1
Estimated H-index: 1
+ 1 AuthorsYouhe Gao3
Estimated H-index: 3
(BNU: Beijing Normal University)
In this report, the urinary proteome from a patient-derived xenograft (PDX) model was examined at the peptide level to study the origins of urinary proteins in tumor-bearing nude mice. Urine was collected from PDX mice before and after colorectal tumor implantation. A total of 4,318 unique peptides were identified, and 78 unambiguous human-origin peptides were discerned in the PDX model urine. Unlike the differential urinary protein composition of tumor-bearing immunocompetent rat models, the di...
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Published on Dec 1, 2019in Scientific Reports 4.01
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Published on Feb 7, 2019in Scientific Reports 4.01
Caleb Busch1
Estimated H-index: 1
(Osaka University),
Taku Wakabayashi16
Estimated H-index: 16
(Osaka University)
+ 7 AuthorsKohji Nishida49
Estimated H-index: 49
(Osaka University)
We investigated changes in retinal vascular area and the foveal avascular zone (FAZ) after intravitreal aflibercept in diabetic macular edema (DME) and the association of these changes with visual outcomes. The retinal vascular area in the superficial capillary plexus (SCP) and the deep capillary plexus (DCP) and the FAZ area were measured using optical coherence tomography angiography (OCTA) in 23 eyes of 23 patients with DME, before and after intravitreal aflibercept. Overall, there was no sig...
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Published on Dec 1, 2019in Scientific Reports 4.01
Alina C Stimmell (FSU: Florida State University), David Baglietto-Vargas21
Estimated H-index: 21
(UCI: University of California, Irvine)
+ 5 AuthorsAaron A. Wilber8
Estimated H-index: 8
(FSU: Florida State University)
In early Alzheimer’s disease (AD) spatial navigation is impaired; however, the precise cause of this impairment is unclear. Recent evidence suggests that getting lost is one of the first impairments to emerge in AD. It is possible that getting lost represents a failure to use distal cues to get oriented in space. Therefore, we set out to look for impaired use of distal cues for spatial orientation in a mouse model of amyloidosis (3xTg-AD). To do this, we trained mice to shuttle to the end of a t...
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Published on May 23, 2019in Scientific Reports 4.01
Neha Dhingra Pottanat (IU: Indiana University), Amy Jayne Chedzoy Brook6
Estimated H-index: 6
(Cardiff University)
+ 15 AuthorsShira H. Cohen (The Research Institute at Nationwide Children's Hospital)
Infectious peritonitis is a common complication in patients undergoing chronic peritoneal dialysis (PD), limiting the duration of PD as a modality for renal replacement therapy and increasing patient morbidity and mortality. Antimicrobial peptides (AMPs) serve critical roles in mucosal defense, but their expression and activity during peritonitis are poorly understood. We hypothesized that AMPs belonging to the Ribonuclease (RNase) A Superfamily are present in peritoneal fluid and increase durin...
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Published on Mar 1, 2019in Scientific Reports 4.01
Jin Shang2
Estimated H-index: 2
(Zhengzhou University),
Shuai Wang (Zhengzhou University)+ 5 AuthorsZhanzheng Zhao7
Estimated H-index: 7
(Zhengzhou University)
LncRNA is reported to have important role in diabetic nephropathy (DN). Here, we aim to identify key lncRNAs of DN using bioinformatics and systems biological methods. Method: Five microarray data sets from Gene Expression Omnibus (GEO) database were included. Probe sets were re-annotated. In the training set, differential expressed genes (DEGs) were identified. Weighted gene co-expression network analysis (WGCNA) was constructed to screen diabetic-related hub genes and reveal their potential bi...
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Published on Feb 14, 2019in Scientific Reports 4.01
Maria Alieva3
Estimated H-index: 3
(UU: Utrecht University),
Verena Leidgens4
Estimated H-index: 4
(UU: Utrecht University)
+ 3 AuthorsJacco van Rheenen (UU: Utrecht University)
The pathogenesis of glioblastoma (GBM) is characterized by highly invasive behavior allowing dissemination and progression. A conclusive image of the invasive process is not available. The aim of this work was to study invasion dynamics in GBM using an innovative in vivo imaging approach. Primary brain tumor initiating cell lines from IDH-wild type GBM stably expressing H2B-Dendra2 were implanted orthotopically in the brains of SCID mice. Using high-resolution time-lapse intravital imaging, tumo...
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Published on May 3, 2019in Scientific Reports 4.01
Elnaz Amanzadeh1
Estimated H-index: 1
(UI: University of Isfahan),
Abolghasem Esmaeili8
Estimated H-index: 8
(UI: University of Isfahan)
+ 3 AuthorsSiamak Beheshti6
Estimated H-index: 6
(UI: University of Isfahan)
Biomedical application of quercetin (QT) as an effective flavonoid has limitations due to its low bioavailability. Superparamagnetic iron oxide nanoparticle (SPION) is a novel drug delivery system that enhances the bioavailability of quercetin. The effect of short time usage of quercetin on learning and memory function and its signaling pathways in the healthy rat is not well understood. The aim of this study was to investigate the effect of free quercetin and in conjugation with SPION on learni...
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