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Scientific Reports
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#1Yuki Murakami (Kansai Medical University)H-Index: 4
#2Yukio Imamura (Osaka University)H-Index: 1
Last. Jun Motoyama (Dodai: Doshisha University)H-Index: 22
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#1Yibo Huang (Kyushu University)H-Index: 2
#2Yujiro HiguchiH-Index: 10
Last. Kaoru TakegawaH-Index: 33
view all 6 authors...
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#1Rodrigo Jácome (UNAM: National Autonomous University of Mexico)H-Index: 7
#2José Alberto Campillo-Balderas (UNAM: National Autonomous University of Mexico)H-Index: 2
Last. Antonio Lazcano (UNAM: National Autonomous University of Mexico)H-Index: 33
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As of today, there is no antiviral for the treatment of the SARS-CoV-2 infection, and the development of a vaccine might take several months or even years The structural superposition of the hepatitis C virus polymerase bound to sofosbuvir, a nucleoside analog antiviral approved for hepatitis C virus infections, with the SARS-CoV polymerase shows that the residues that bind to the drug are present in the latter Moreover, a multiple alignment of several SARS-CoV-2, SARS and MERS-related coronavir...
2 CitationsSource
#1Morten Schou (NTNU: Norwegian University of Science and Technology)H-Index: 24
Last. Daniel Kondziella (UCPH: University of Copenhagen)H-Index: 22
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The clinical significance of anti-neuronal antibodies for psychiatric disorders is controversial. We investigated if a positive anti-neuronal antibody status at admission to acute psychiatric inpatient care was associated with a more severe neuropsychiatric phenotype and more frequent abnormalities during clinical work-up three years later. Patients admitted to acute psychiatric inpatient care who tested positive for N-methyl-D-aspartate receptor (NMDAR), contactin-associated protein 2 (CASPR2) ...
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#1Lisa Kapper (UNAM: National Autonomous University of Mexico)H-Index: 2
#2Vincent Serneels (University of Fribourg)H-Index: 7
Last. Ruben Cejudo Ruiz (UNAM: National Autonomous University of Mexico)H-Index: 4
view all 9 authors...
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#1Spencer B. Mamer (UIUC: University of Illinois at Urbana–Champaign)H-Index: 2
#2Si Chen (UIUC: University of Illinois at Urbana–Champaign)H-Index: 5
Last. P. I. Imoukhuede (UIUC: University of Illinois at Urbana–Champaign)H-Index: 14
view all 7 authors...
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#1Bhanu Prasad Venkatesulu (University of Texas MD Anderson Cancer Center)H-Index: 5
#2Amrish Sharma (University of Texas MD Anderson Cancer Center)H-Index: 7
Last. Sunil KrishnanH-Index: 19
view all 10 authors...
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#1Tomáš Dostálek (Charles University in Prague)H-Index: 8
#2Maan Bahadur Rokaya (Charles University in Prague)H-Index: 11
Last. Zuzana Münzbergová (Charles University in Prague)H-Index: 31
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Climate warming is expected to significantly affect plant–herbivore interactions. Even though direct effects of temperature on herbivores were extensively studied, indirect effects of temperature (acting via changes in host plant quality) on herbivore performance have rarely been addressed. We conducted multiple-choice feeding experiments with generalist herbivore Schistocerca gregaria feeding on six species of genus Impatiens cultivated at three different temperatures in growth chambers and a c...
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#1Prasad G. Kamble (Uppsala University)H-Index: 3
#2Susanne Hetty (Uppsala University)
Last. Jan W. Eriksson (Uppsala University)H-Index: 26
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CRISPR/Cas9 has revolutionized the genome-editing field. So far, successful application in human adipose tissue has not been convincingly shown. We present a method for gene knockout using electroporation in preadipocytes from human adipose tissue that achieved at least 90% efficiency without any need for selection of edited cells or clonal isolation. We knocked out the FKBP5 and PPARG genes in preadipocytes and studied the resulting phenotypes. PPARG knockout prevented differentiation into adip...
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#1Anna Ewa Kędzierska (PAN: Polish Academy of Sciences)H-Index: 3
#2Daria Lorek (PAN: Polish Academy of Sciences)H-Index: 1
Last. Anna Chełmońska-Soyta (Wroclaw University of Environmental and Life Sciences)H-Index: 9
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The imbalance in immune tolerance may cause the variety of reproductive failures. An intravenous immunoglobulin infusion (IVIg) therapy is used to improve the live birth rate in women suffering from recurrent pregnancy loss, recurrent spontaneous abortions and recurrent implantation failures. However, the results of IVIg studies are still inconclusive as IVIg infusion in women suffering from pregnancy loss is sometimes ineffective. One of the mechanisms of action of this treatment is inhibition ...
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