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Risk of Latent Tuberculosis Reactivation After Hematopoietic cell Transplantation

Published on Aug 16, 2019in Clinical Infectious Diseases9.055
· DOI :10.1093/cid/ciz048
Matthew P. Cheng10
Estimated H-index: 10
(Harvard University),
Amanda E. Kusztos3
Estimated H-index: 3
(Harvard University)
+ 7 AuthorsFrancisco M. Marty44
Estimated H-index: 44
(Harvard University)
Abstract
  • References (9)
  • Citations (3)
References9
Newest
#1Ibrahim Abubakar (UCL Institute for Global Health)H-Index: 55
#2Francis Drobniewski (Imperial College London)H-Index: 56
Last. F SandersonH-Index: 1
view all 47 authors...
Summary Background Tackling tuberculosis requires testing and treatment of latent tuberculosis in high-risk groups. The aim of this study was to estimate the predictive values of the tuberculin skin test (TST) and two interferon-γ release assays (IGRAs) for the development of active tuberculosis in high-risk groups—ie, people in recent contact with active tuberculosis cases and from high-burden countries. Method In this prospective cohort study, we recruited participants from 54 centres (eg, cli...
16 CitationsSource
#1Marcel A. Behr (MUHC: McGill University Health Centre)H-Index: 52
#2Paul H. Edelstein (UPenn: University of Pennsylvania)H-Index: 48
Last. Lalita Ramakrishnan (LMB: Laboratory of Molecular Biology)H-Index: 43
view all 3 authors...
Tuberculosis has a much shorter incubation period than is widely thought, say Marcel A Behr and colleagues , and this has implications for prioritising research and public health strategies
42 CitationsSource
#1Dick Menzies (BC Centre for Disease Control)H-Index: 2
#2Menonli Adjobimey (BC Centre for Disease Control)H-Index: 2
Last. Andrea Benedetti (BC Centre for Disease Control)H-Index: 1
view all 29 authors...
Abstract Background A 9-month regimen of isoniazid can prevent active tuberculosis in persons with latent tuberculosis infection. However, the regimen has been associated with poor adherence rates and with toxic effects. Methods In an open-label trial conducted in nine countries, we randomly assigned adults with latent tuberculosis infection to receive treatment with a 4-month regimen of rifampin or a 9-month regimen of isoniazid for the prevention of confirmed active tuberculosis within 28 mont...
45 CitationsSource
#1Yao-Chung Liu (NYMU: National Yang-Ming University)H-Index: 7
#2Chi-Jung Wu (Taipei Veterans General Hospital)H-Index: 2
Last. Jin-Hwang Liu (NYMU: National Yang-Ming University)H-Index: 25
view all 12 authors...
Abstract Background Mycobacterial infections are important and potentially life-threatening complications after organ transplantations. Notably, for the recipients of allogeneic hematopoietic stem cell transplantation (HSCT), there are a few supporting results to explore post-transplant mycobacterial infections. Taiwan is a high endemic area of the infection. We aim to investigate the incidence, risk factors, and survival of post-transplant mycobacterial infections, including mycobacterium tuber...
2 CitationsSource
#1Narendra AgrawalH-Index: 4
#2Mukul AggarwalH-Index: 4
Last. Dinesh BhuraniH-Index: 4
view all 7 authors...
4 CitationsSource
#1C. WhalenH-Index: 1
6 Citations
#1Matthew P. Cheng (MUHC: McGill University Health Centre)H-Index: 10
#2Abou Chakra Cn (JGH: Jewish General Hospital)H-Index: 1
Last. Christina Greenaway (McGill University)H-Index: 19
view all 7 authors...
Abstract Cancer is a known risk factor for developing active tuberculosis (TB). We determined the incidence and relative risk of active TB in cancer patients compared to the general population. Electronic databases were searched up to December 2015: Medline, Medline InProcess, EMBASE, PubMed, the Cochrane Database of Systematic Reviews, Cancerlit, and Web of Science. Studies of pathologically confirmed cancer patients were included if active TB was identified concurrently or after the diagnosis....
24 CitationsSource
BACKGROUND: Tuberculosis (TB) is a serious problem for patients undergoing haematopoietic stem cell transplantation (HSCT) in TB-endemic areas; however, data on these patients are limited. METHODS: We obtained data on 2040 HSCT recipients from the Registry of Catastrophic Illness in Taiwan from 1997 to 2006. We also obtained data on age-, sex- and enrolment date-matched controls from the Longitudinal Health Insurance Database. The cumulative incidence of active TB in HSCT recipients and controls...
20 CitationsSource
#1Christie Y. Jeon (Harvard University)H-Index: 21
#2Megan Murray (Harvard University)H-Index: 57
Background Several studies have suggested that diabetes mellitus (DM) increases the risk of active tuberculosis (TB). The rising prevalence of DM in TB-endemic areas may adversely affect TB control. We conducted a systematic review and a meta-analysis of observational studies assessing the association of DM and TB in order to summarize the existing evidence and to assess methodological quality of the studies. Methods and Findings We searched the PubMed and EMBASE databases to identify observatio...
675 CitationsSource
Cited By3
Newest
#1Joung Ha Park (UOU: University of Ulsan)H-Index: 1
#2Eun-Ji Choi (UOU: University of Ulsan)H-Index: 7
Last. Tae Sun Shim (UOU: University of Ulsan)H-Index: 33
view all 12 authors...
Source
#1Joumana Kmeid (University of Texas MD Anderson Cancer Center)H-Index: 2
#2Prathit A. Kulkarni (BCM: Baylor College of Medicine)H-Index: 4
Last. Roy F. Chemaly (University of Texas MD Anderson Cancer Center)H-Index: 36
view all 8 authors...
Morbidity and mortality from Mycobacterium tuberculosis (Mtb) infection remain significant in cancer patients. We evaluated clinical characteristics, management, and outcomes in patients with active Mtb infection at our institution who had cancer or suspicion of cancer. We retrospectively examined medical records of all patients with laboratory-confirmed active Mtb infection diagnosed between 2006 and 2014. A total of 52 patients with laboratory-confirmed active Mtb infection were identified dur...
Source
#1Marcel A. Behr (McGill University)H-Index: 52
#2Paul H. Edelstein (UPenn: University of Pennsylvania)H-Index: 48
Last. Lalita Ramakrishnan (LMB: Laboratory of Molecular Biology)H-Index: 43
view all 3 authors...
People with immunoreactivity to tuberculosis are thought to have lifelong asymptomatic infection and remain at risk for active tuberculosis. Marcel A Behr and colleagues argue that most of these people are no longer infected
5 CitationsSource
#1Nina Singh (University of Pittsburgh)H-Index: 76
Source
#1Tyler D. Bold (UMN: University of Minnesota)H-Index: 7
#2Matthew P. Cheng (Harvard University)H-Index: 10
Last. Francisco M. Marty (Harvard University)H-Index: 44
view all 3 authors...
Source
#1Matthew P. Cheng (Harvard University)H-Index: 10
#2Francisco M. Marty (Harvard University)H-Index: 44
Source
#1Jenny R AronsonH-Index: 1
#2Andrew R. Rezvani (Stanford University)H-Index: 14
Last. Aruna K. SubramanianH-Index: 17
view all 3 authors...
1 CitationsSource