Wiring the depressed brain: optogenetic and chemogenetic circuit interrogation in animal models of depression
Abstract
The advent of optogenetics and chemogenetics has revolutionized the study of neural circuit mechanisms of behavioral dysregulation in psychiatric disease. These powerful technologies allow manipulation of specific neurons to determine causal relationships between neuronal activity and behavior. Optogenetic tools have been key to mapping the circuitry underlying depression-like behavior in animal models, clarifying the contribution of the ventral...
Paper Details
Title
Wiring the depressed brain: optogenetic and chemogenetic circuit interrogation in animal models of depression
Published Date
Dec 5, 2018
Journal
Volume
44
Issue
6
Pages
1013 - 1026
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