Prefrontal-accumbens opioid plasticity: Implications for relapse and dependence
Abstract
In addiction, an individual's ability to inhibit drug seeking and drug taking is thought to reflect a pathological strengthening of drug-seeking behaviors or impairments in the capacity to control maladaptive behavior. These processes are not mutually exclusive and reflect drug-induced modifications within prefrontal cortical and nucleus accumbens circuits, however unlike psychostimulants such as cocaine, far less is known about the temporal,...
Paper Details
Title
Prefrontal-accumbens opioid plasticity: Implications for relapse and dependence
Published Date
Jan 1, 2019
Journal
Volume
139
Pages
158 - 165
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Notes
History