Dickkopf-3 (DKK3) in Urine Identifies Patients with Short-Term Risk of eGFR Loss

The individual course of CKD may vary, and improved methods for identifying which patients will experience short-term eGFR loss are needed. Assessing urinary Dickkopf-3 (DKK3), a stress-induced tubular epithelia-derived profibrotic glycoprotein, may provide information about ongoing tubulointerstitial fibrosis and short-term eGFR loss.To investigate urinary DKK3's potential as a biomarker of short-term eGFR loss (over 12 months), we...