MIM1, the Mcl-1 – specific BH3 mimetic induces apoptosis in human U87MG glioblastoma cells
Abstract
Glioblastoma multiforme (GBM) is the most common and high aggressive malignant brain tumor. Despite evolving oncology treatment and novel chemotherapeutic agents the median survival of patients diagnosed with GBM is only 12-15 months. This grim fact highlights necessity to identify new drugs that could improve the effectiveness of GBM patients treatment. MIM1 is a specific low molecular Mcl-1 protein inhibitor able to induce Mcl-1-dependent...
Paper Details
Title
MIM1, the Mcl-1 – specific BH3 mimetic induces apoptosis in human U87MG glioblastoma cells
Published Date
Dec 1, 2018
Journal
Volume
53
Pages
126 - 135
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Notes
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