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Ewa Buszman
University of Silesia in Katowice
97Publications
18H-index
803Citations
Publications 97
Newest
#1Dorota Wrześniok (University of Silesia in Katowice)H-Index: 6
#2Jakub Rok (University of Silesia in Katowice)H-Index: 3
Last.Ewa Buszman (University of Silesia in Katowice)H-Index: 18
view all 9 authors...
#1Michalina Respondek (Medical University of Silesia)H-Index: 2
#2Artur Beberok (Medical University of Silesia)H-Index: 9
Last.Ewa Buszman (Medical University of Silesia)H-Index: 18
view all 6 authors...
Abstract Glioblastoma multiforme (GBM) is the most common and high aggressive malignant brain tumor. Despite evolving oncology treatment and novel chemotherapeutic agents the median survival of patients diagnosed with GBM is only 12–15 months. This grim fact highlights necessity to identify new drugs that could improve the effectiveness of GBM patients treatment. MIM1 is a specific low molecular Mcl-1 protein inhibitor able to induce Mcl-1-dependent cancer cells death. The aim of this study was ...
#1Agata Kabała-Dzik (University of Silesia in Katowice)H-Index: 12
#2Anna Rzepecka-Stojko (University of Silesia in Katowice)H-Index: 7
Last.Jerzy Stojko (University of Silesia in Katowice)H-Index: 11
view all 6 authors...
Epithelium mammary carcinoma is a cancer with a high death rate among women. One factor having a significant impact on metastasis is cell migration. The aim of this study was to compare migration r...
#1Dorota Wrześniok (University of Silesia in Katowice)H-Index: 6
#2Zuzanna Rzepka (University of Silesia in Katowice)H-Index: 3
Last.Ewa Buszman (University of Silesia in Katowice)H-Index: 18
view all 7 authors...
Abstract Coffee is one of the most popular beverages consumed worldwide and therefore even small effects of coffee bioactive compounds on cellular homeostasis could have a large impact on public health. Recent cohort health studies have shown an impressive inverse correlation between caffeinated coffee consumption and malignant melanoma risk. The aim of presented study was to examine the effect of caffeine on cell viability and glutathione status of melanotic (COLO829) and amelanotic (C32) melan...
#1Michał Otręba (Medical University of Silesia)H-Index: 9
#2Artur Beberok (Medical University of Silesia)H-Index: 9
Last.Ewa Buszman (Medical University of Silesia)H-Index: 18
view all 4 authors...
Purpose Fluphenazine and prochlorperazine as phenothiazine-class antipsychotic drugs are widely used to treat schizophrenia, however their use is associated with significant side effects such as extrapyramidal symptoms, as well as ocular and skin disorders. Our goal was to determine the effect of fluphenazine and prochlorperazine on cell viability and melanogenesis in lightly pigmented normal human melanocytes.
#1Agata Kabała-Dzik (University of Silesia in Katowice)H-Index: 12
#2Anna Rzepecka-Stojko (University of Silesia in Katowice)H-Index: 7
Last.Jerzy Stojko (University of Silesia in Katowice)H-Index: 11
view all 7 authors...
Breast cancer is one of the most common causes of mortality in women. Flavonoids, among other compounds, are bioactive constituents of propolis. In this comparative study, we investigated the effects of flavonoids apigenin (API), genistein (GEN), hesperidin (HES), naringin (NAR) and quercetin (QUE) on the proliferation, apoptosis, and cell cycle of two different human cancer cells - MDA-MB-231, estrogen-negative, and MCF-7, estrogen-positive receptor breast carcinoma cells. Many cytotoxic report...
#1Jakub Rok (Medical University of Silesia)H-Index: 7
#2Dorota Wrześniok (Medical University of Silesia)H-Index: 13
Last.Ewa Buszman (Medical University of Silesia)H-Index: 18
view all 6 authors...
Abstract Oxytetracycline is a broad-spectrum antibiotic, used in dermatology and veterinary medicine. Like other tetracyclines, it may evoke skin phototoxic reactions related to generation of reactive oxygen species (ROS). Melanins are biopolymers synthesised in melanocytes – highly specialised cells, localised in the basal layer of epidermis. Production of melanin is a defence mechanism against harmful effects of UV radiation, ROS and many chemical substances, including drugs. In the present st...
#1Artur Beberok (Medical University of Silesia)H-Index: 9
#2Dorota Wrześniok (Medical University of Silesia)H-Index: 13
Last.Ewa Buszman (Medical University of Silesia)H-Index: 18
view all 6 authors...
#1Artur Beberok (Medical University of Silesia)H-Index: 9
#2Dorota Wrześniok (Medical University of Silesia)H-Index: 13
Last.Ewa Buszman (Medical University of Silesia)H-Index: 18
view all 8 authors...
Abstract Background Low effectiveness of anti-melanoma therapies makes it necessary to search for new drugs that could improve or replace the standard chemotherapy. Fluoroquinolones are a group of synthetic antibiotics, used in the treatment of wide range of bacterial infections. Moreover, this class of antibiotics has shown promising anti-tumor activity in several cancer cell lines. The aim of this study was to examine the effect of ciprofloxacin on cell viability, apoptosis and cell cycle dist...
#2Jerzy StojkoH-Index: 11
Last.Ewa BuszmanH-Index: 18
view all 4 authors...
The aim of this study was to determine the effect of polyphenol-rich ethanol extract of bee pollen (EEP) on atherosclerosis induced by a high-fat diet in ApoE-knockout mice. EEP was given with feed in two doses of 0.1 and 1 g/kg body mass (BM). The studies have been conducted in a period of 16 weeks. The following factors were estimated: total cholesterol (TC), oxidized low density lipoproteins (ox-LDL), asymmetric dimethylarginine (ADMA), angiotensin-converting enzyme (ACE) and angiotensin II (...
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