Toxicology in Vitro
Papers 5211
1 page of 522 pages (5,211 results)
#1Barbara Davis (UCR: University of California, Riverside)H-Index: 6
#2Vivian To (UCR: University of California, Riverside)
Last.Prue Talbot (UCR: University of California, Riverside)H-Index: 28
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Abstract This study compared the cytotoxicity of IQOS aerosols to smoke from Marlboro Red (MR) and 3R4F reference cigarettes. Aerosol/smoke solutions were tested as the gas vapor phase (GVP), particulate phase (total particulate matter or TPM), or whole aerosol/smoke (WA), the latter being what smokers actually inhale. Cytotoxicities were evaluated using the LDH, MTT and neutral red uptake (NRU) assays in conjunction with eight different cell types, mainly from the respiratory system. Most test ...
#1Ke WangH-Index: 15
#2Ping Zou (Nanjing Medical University)
Last.Ting Zhang (Nanjing Medical University)H-Index: 9
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Abstract Triple negative breast cancer (TNBC), an aggressive form of breast cancer, has high rate of metastasis and which is the main cause of poor outcomes for such disease. The acquisition of invasive properties such as epithelial mesenchymal transition (EMT) and anoikis resistance is estimated to be the critical step in TNBC metastasis. Therefore, targeting these metastatic processes may contribute to the control of TNBC metastasis. In this study, investigations were conducted into the effect...
#1Wonhyoung Park (KU: Korea University)
#2Min Young Park (KU: Korea University)
Last.Whasun Lim (Kookmin University)H-Index: 15
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Abstract Mammary gland epithelial cells play a key role in milk production in dairy cattle, which are prone to feed contamination from microorganisms, especially pathogenic fungi and their mycotoxin products. When mycotoxins enter the body, they cause a reduction in feed intake and milk production, leading to the retardation of growth and productivity in dairy cattle. Among them, aflatoxin B1 is a ubiquitous food contaminant frequently found in stored crops, which are used as animal feed, and ca...
#1Magdalena Zdybel (Medical University of Silesia)H-Index: 5
#2Ewa Chodurek (Medical University of Silesia)H-Index: 9
Last.Barbara Pilawa (Medical University of Silesia)H-Index: 15
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Abstract Malignant melanoma is the most aggressive and lethal form of skin cancer. Therefore the search for new methods of the treatment for melanoma is needed. In this work simvastatin was tested as the substance of potential anticancer activity. The aim of this study was to determine the effect of simvastatin in different concentration on free radicals in A-375 human melanoma malignum cells. Free radicals and growth of A-375 melanoma cells cultured without and with simvastatin were examined. F...
#1Saniyya Khan (AMU: Aligarh Muslim University)H-Index: 1
#2Imrana Naseem (AMU: Aligarh Muslim University)H-Index: 15
Abstract Photosensitisation of riboflavin (Rf) activates aminophylline (Am) resulting into the formation of a highly pro-oxidant Am-Rf system. We have previously shown its macromolecular damaging response in human peripheral lymphocytes, however, its potential inside a cancer cell is yet to be explored. Since, altered redox status of a cancer cell is a reliable therapeutic window in designing anticancer strategies, therefore, it's imperative to investigate whether the reactive oxygen species (RO...
#1David M. Brown (Heriot-Watt University)H-Index: 35
#2Pernille Høgh Danielsen (UCPH: University of Copenhagen)H-Index: 23
Last.Ali Kermanizadeh (Heriot-Watt University)H-Index: 19
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Abstract The rapid expansion of the incorporation of nano-sized materials in consumer products overlaps with the necessity for high-throughput reliable screening tools for the identification of the potential hazardous properties of the nanomaterials. The ToxTracker assay (mechanism-based reporter assay based on embryonic stem cells that uses GFP-tagged biomarkers for detection of DNA damage, oxidative stress and general cellular stress) is one such tool, which could prove useful in the field of ...