T274. EEG Asymmetry During Emotional Challenge Predicts Future Depressive Symptoms

Research supports electroencephalographic (EEG) asymmetry as a promising biomarker of risk for depression. Greater depressive symptoms are linked to greater right than left prefrontal cortex (PFC) activity, a relationship that is more robust when EEG is recorded during emotional challenge as opposed to a resting state. Although PFC asymmetry recorded at rest also predicts future depressive symptoms in never-depressed individuals, bolstering its...