Effects of MiR‐137 genetic risk score on brain volume and cortical measures in patients with schizophrenia and controls

Volume: 177, Issue: 3, Pages: 369 - 376
Published: Feb 8, 2018
Abstract
Multiple genome‐wide association studies of schizophrenia have implicated genetic variants within the gene encoding microRNA‐137. As risk variants within or regulated by MIR137 have been implicated in memory performance, we investigated the additive effects of schizophrenia‐associated risk variants in genes empirically regulated by MIR137 on brain regions associated with memory function. A polygenic risk score (PRS) was calculated (at a p = 0.05...
Paper Details
Title
Effects of MiR‐137 genetic risk score on brain volume and cortical measures in patients with schizophrenia and controls
Published Date
Feb 8, 2018
Volume
177
Issue
3
Pages
369 - 376
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