Original paper
Structural basis for xenobiotic extrusion by eukaryotic MATE transporter
Abstract
Mulitidrug and toxic compound extrusion (MATE) family transporters export xenobiotics to maintain cellular homeostasis. The human MATE transporters mediate the excretion of xenobiotics and cationic clinical drugs, whereas some plant MATE transporters are responsible for aluminum tolerance and secondary metabolite transport. Here we report the crystal structure of the eukaryotic MATE transporter from Arabidopsis thaliana , at 2.6 Å resolution....
Paper Details
Title
Structural basis for xenobiotic extrusion by eukaryotic MATE transporter
Published Date
Nov 21, 2017
Journal
Volume
8
Issue
1
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Notes
History