Nature Communications
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#1Changhai Lei ('SMMU': Second Military Medical University)H-Index: 5
#2Kewen Qian ('SMMU': Second Military Medical University)H-Index: 2
Last. Shi Hu ('SMMU': Second Military Medical University)H-Index: 9
view all 7 authors...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China, at the end of 2019, and there are currently no specific antiviral treatments or vaccines available. SARS-CoV-2 has been shown to use the same cell entry receptor as SARS-CoV, angiotensin-converting enzyme 2 (ACE2). In this report, we generate a recombinant protein by connecting the extracellular domain of human ACE2 to the Fc region of the human immunoglobulin IgG1. A fusion protein containing an ACE2 mutant wi...
17 CitationsSource
#1Nicolai Franzmeier (LMU: Ludwig Maximilian University of Munich)H-Index: 11
#1Alzheimer’s Disease Neuroimaging Initiative (LMU: Ludwig Maximilian University of Munich)H-Index: 1
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In Alzheimer’s diseases (AD), tau pathology is strongly associated with cognitive decline. Preclinical evidence suggests that tau spreads across connected neurons in an activity-dependent manner. Supporting this, cross-sectional AD studies show that tau deposition patterns resemble functional brain networks. However, whether higher functional connectivity is associated with higher rates of tau accumulation is unclear. Here, we combine resting-state fMRI with longitudinal tau-PET in two independe...
4 CitationsSource
#1Hongwei Tan (Aalto University)H-Index: 1
#1Hongwei Tan (Aalto University)H-Index: 9
Last. Sebastiaan van Dijken (Aalto University)H-Index: 25
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The integration and cooperation of mechanoreceptors, neurons and synapses in somatosensory systems enable humans to efficiently sense and process tactile information. Inspired by biological somatosensory systems, we report an optoelectronic spiking afferent nerve with neural coding, perceptual learning and memorizing capabilities to mimic tactile sensing and processing. Our system senses pressure by MXene-based sensors, converts pressure information to light pulses by coupling light-emitting dio...
1 CitationsSource
#1Vinicius Oliari (TU/e: Eindhoven University of Technology)H-Index: 1
#2Erik Agrell (Chalmers University of Technology)H-Index: 30
Last. Alex Alvarado (TU/e: Eindhoven University of Technology)H-Index: 22
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Communication using the optical fibre channel can be challenging due to nonlinear effects that arise in the optical propagation. These effects represent physical processes that originate from light propagation in optical fibres. To obtain fundamental understandings of these processes, mathematical models are typically used. These models are based on approximations of the nonlinear Schrodinger equation, the differential equation that governs the propagation in an optical fibre. All available mode...
#1Kyoko WatanabeH-Index: 14
Last. Danielle PosthumaH-Index: 76
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The original version of this Article contained an error in Fig. 5 and Supplementary Fig. 12, in which the colours of the bar plots at the top of the heatmaps were incorrectly given, leading to incorrect mapping of the plots to the corresponding dataset based on the dataset legend. The correct version of Fig. 5 is. (Figure Presented.).
#1Bayan Karimi (Aalto University)H-Index: 5
#2Fredrik Brange (Lund University)H-Index: 4
Last. Jukka P. Pekola (Aalto University)H-Index: 36
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Quantum calorimetry, the thermal measurement of quanta, is a method of choice for ultrasensitive radiation detection ranging from microwaves to gamma rays. The fundamental temperature fluctuations of the calorimeter, dictated by the coupling of it to the heat bath, set the ultimate lower bound of its energy resolution. Here we reach this limit of fundamental equilibrium fluctuations of temperature in a nanoscale electron calorimeter, exchanging energy with the phonon bath at very low temperature...
5 CitationsSource
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Molecular biology
Cell biology