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Nature Communications
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11.88
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Published on Apr 23, 2019in Nature Communications11.88
Koichi Kikuchi11
Estimated H-index: 11
(Tohoku University),
Koichi Kikuchi (Tohoku University)+ 53 AuthorsKoki Mise11
Estimated H-index: 11
(Okayama University)
Diabetic kidney disease is a major cause of renal failure that urgently necessitates a breakthrough in disease management. Here we show using untargeted metabolomics that levels of phenyl sulfate, a gut microbiota-derived metabolite, increase with the progression of diabetes in rats overexpressing human uremic toxin transporter SLCO4C1 in the kidney, and are decreased in rats with limited proteinuria. In experimental models of diabetes, phenyl sulfate administration induces albuminuria and podoc...
Published in Nature Communications11.88
Lun Zhao (HAU: Huazhong Agricultural University), Shuangqi Wang (HAU: Huazhong Agricultural University)+ -3 AuthorsZhe Hu (HAU: Huazhong Agricultural University)
Insight into high-resolution three-dimensional genome organization and its effect on transcription remains largely elusive in plants. Here, using a long-read ChIA-PET approach, we map H3K4me3- and RNA polymerase II (RNAPII)-associated promoter–promoter interactions and H3K9me2-marked heterochromatin interactions at nucleotide/gene resolution in rice. The chromatin architecture is separated into different independent spatial interacting modules with distinct transcriptional potential and covers a...
Published on Dec 1, 2019in Nature Communications11.88
Xiaoliang Yan (TUT: Taiyuan University of Technology), Wei Sun8
Estimated H-index: 8
(ZJU: Zhejiang University)
+ 19 AuthorsAlexandra V. Tavasoli1
Estimated H-index: 1
(U of T: University of Toronto)
Two-dimensional (2D) materials are of considerable interest for catalyzing the heterogeneous conversion of CO2 to synthetic fuels. In this regard, 2D siloxene nanosheets, have escaped thorough exploration, despite being composed of earth-abundant elements. Herein we demonstrate the remarkable catalytic activity, selectivity, and stability of a nickel@siloxene nanocomposite; it is found that this promising catalytic performance is highly sensitive to the location of the nickel component, being on...
Published on Jan 30, 2019in Nature Communications11.88
Raghav R. Poudyal1
Estimated H-index: 1
(PSU: Pennsylvania State University),
Rebecca M. Guth-Metzler1
Estimated H-index: 1
(Georgia Institute of Technology)
+ 3 AuthorsPhilip C. Bevilacqua42
Estimated H-index: 42
(PSU: Pennsylvania State University)
Membraneless compartments, such as complex coacervates, have been hypothesized as plausible prebiotic micro-compartments due to their ability to sequester RNA; however, their compatibility with essential RNA World chemistries is unclear. We show that such compartments can enhance key prebiotically-relevant RNA chemistries. We demonstrate that template-directed RNA polymerization is sensitive to polycation identity, with polydiallyldimethylammonium chloride (PDAC) outperforming poly(allylamine), ...
Published on Jan 1, 2019in Nature Communications11.88
Xuping Li2
Estimated H-index: 2
(Fudan University),
Gleb V. Baryshnikov20
Estimated H-index: 20
(KTH: Royal Institute of Technology)
+ 5 AuthorsLiangliang Zhu24
Estimated H-index: 24
(Fudan University)
Visualized sensing through fluorescence signals is a powerful method for chemical and physical detection. However, the utilization of fluorescent molecular probes still suffers from lack of precise ...
Published on Dec 1, 2019in Nature Communications11.88
C. Elias (University of Montpellier), Pierre Valvin15
Estimated H-index: 15
(University of Montpellier)
+ 9 AuthorsS. V. Novikov12
Estimated H-index: 12
(University of Nottingham)
Hexagonal boron nitride is a large band-gap insulating material which complements the electronic and optical properties of graphene and the transition metal dichalcogenides. However, the intrinsic optical properties of monolayer boron nitride remain largely unexplored. In particular, the theoretically expected crossover to a direct-gap in the limit of the single monolayer is presently not confirmed experimentally. Here, in contrast to the technique of exfoliating few-layer 2D hexagonal boron nit...
Published on Dec 1, 2019in Nature Communications11.88
JinSeok Park7
Estimated H-index: 7
(Yale University),
Deok Ho Kim39
Estimated H-index: 39
(UW: University of Washington)
+ 5 AuthorsAndre Levchenko50
Estimated H-index: 50
(Yale University)
Collective cell migration occurs in many patho-physiological states, including wound healing and invasive cancer growth. The integrity of the expanding epithelial sheets depends on extracellular cues, including cell-cell and cell-matrix interactions. We show that the nano-scale topography of the extracellular matrix underlying epithelial cell layers can strongly affect the speed and morphology of the fronts of the expanding sheet, triggering partial and complete epithelial-mesenchymal transition...
Published in Nature Communications11.88
Mareike Grotheer7
Estimated H-index: 7
(Stanford University),
Zonglei Zhen11
Estimated H-index: 11
(BNU: Beijing Normal University)
+ -3 AuthorsKalanit Grill-Spector38
Estimated H-index: 38
(Stanford University)
Math and reading involve distributed brain networks and have both shared (e.g. encoding of visual stimuli) and dissociated (e.g. quantity processing) cognitive components. Yet, to date, the shared vs. dissociated gray and white matter substrates of the math and reading networks are unknown. Here, we define these networks and evaluate the structural properties of their fascicles using functional MRI, diffusion MRI, and quantitative MRI. Our results reveal that there are distinct gray matter regio...
Published in Nature Communications11.88
Eadaoin Harney11
Estimated H-index: 11
(Harvard University),
Ayushi Nayak1
Estimated H-index: 1
(MPG: Max Planck Society)
+ -3 AuthorsR.L. Bernardos8
Estimated H-index: 8
(Harvard University)
Situated at over 5,000 meters above sea level in the Himalayan Mountains, Roopkund Lake is home to the scattered skeletal remains of several hundred individuals of unknown origin. We report genome-wide ancient DNA for 38 skeletons from Roopkund Lake, and find that they cluster into three distinct groups. A group of 23 individuals have ancestry that falls within the range of variation of present-day South Asians. A further 14 have ancestry typical of the eastern Mediterranean. We also identify on...
Published on Dec 1, 2019in Nature Communications11.88
J. M. Rickman21
Estimated H-index: 21
(Lehigh University),
Helen M. Chan37
Estimated H-index: 37
(Lehigh University)
+ 4 AuthorsG. Balasubramanian (Lehigh University)
The field of multi-principal element or (single-phase) high-entropy (HE) alloys has recently seen exponential growth as these systems represent a paradigm shift in alloy development, in some cases exhibiting unexpected structures and superior mechanical properties. However, the identification of promising HE alloys presents a daunting challenge given the associated vastness of the chemistry/composition space. We describe here a supervised learning strategy for the efficient screening of HE alloy...
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