Nature Communications
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Published on Mar 4, 2019in Nature Communications 12.35
Zhu Wang6
Estimated H-index: 6
(University of Wisconsin-Madison),
Soongyu Yi3
Estimated H-index: 3
(University of Wisconsin-Madison)
+ 10 AuthorsAlireza Shahsafi2
Estimated H-index: 2
(University of Wisconsin-Madison)
Miniaturized spectrometers have significant potential for portable applications such as consumer electronics, health care, and manufacturing. These applications demand low cost and high spectral resolution, and are best enabled by single-shot free-space-coupled spectrometers that also have sufficient spatial resolution. Here, we demonstrate an on-chip spectrometer that can satisfy all of these requirements. Our device uses arrays of photodetectors, each of which has a unique responsivity with ri...
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Published on Jan 22, 2019in Nature Communications 12.35
Adam Kim3
Estimated H-index: 3
(University of Maryland, Baltimore),
Jean Popovici5
Estimated H-index: 5
(Pasteur Institute)
+ 1 AuthorsDavid Serre16
Estimated H-index: 16
(University of Maryland, Baltimore)
Studies of Plasmodium vivax gene expression are complicated by the lack of in vitro culture system and the difficulties associated with studying clinical infections that often contain multiple clones and a mixture of parasite stages. Here, we characterize the transcriptomes of P. vivax parasites from 26 malaria patients. We show that most parasite mRNAs derive from trophozoites and that the asynchronicity of P. vivax infections is therefore unlikely to confound gene expression studies. Analyses ...
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Published on Feb 14, 2019in Nature Communications 12.35
Lin Wang4
Estimated H-index: 4
(Tongji University),
Yilong Zhou6
Estimated H-index: 6
(Tongji University)
+ 17 AuthorsJuhao Yang (Pasteur Institute)
Excessive or uncontrolled release of proinflammatory cytokines caused by severe viral infections often results in host tissue injury or even death. Phospholipase C (PLC)s degrade phosphatidylinositol-4, 5-bisphosphate (PI(4,5)P2) lipids and regulate multiple cellular events. Here, we report that PLCβ2 inhibits the virus-induced expression of pro-inflammatory cytokines by interacting with and inhibiting transforming growth factor-β-activated kinase 1 (TAK1) activation. Mechanistically, PI(4,5)P2 ...
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Published on Mar 5, 2019in Nature Communications 12.35
Bo Wu16
Estimated H-index: 16
(Nanyang Technological University),
Haifeng Yuan10
Estimated H-index: 10
(Katholieke Universiteit Leuven)
+ 13 AuthorsAnkur Solanki7
Estimated H-index: 7
(Nanyang Technological University)
The original version of this article incorrectly listed the present address of Bo Wu as ‘Present address: Institute of Electronic Paper Displays, South China Academy of Advanced Optoelectronics, South China Normal University, Guangzhou, Guangdong Province 510006, China’. This is the author’s primary affiliation. This has been corrected in both the PDF and HTML versions of the article.
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Published on Jan 8, 2019in Nature Communications 12.35
Shuta Asai1
Estimated H-index: 1
(Sainsbury Laboratory),
Oliver J. Furzer4
Estimated H-index: 4
(University of North Carolina at Chapel Hill)
+ 6 AuthorsJonathan D. G. Jones110
Estimated H-index: 110
(Sainsbury Laboratory)
The original version of this article contained an error in the author affiliations. Oliver J. Furzer was incorrectly associated with Department of Plant Sciences, College of Life Sciences, Wuhan University, 430072, Wuhan, China.This has now been corrected in the HTML version of the article. The PDF version of the article was correct at the time of publication.Furthermore, the original version of this article stated that correspondence and requests for materials should be addressed to Heidelberg....
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Published on Jan 30, 2019in Nature Communications 12.35
Raghav R. Poudyal1
Estimated H-index: 1
(Pennsylvania State University),
Rebecca M. Guth-Metzler (Georgia Institute of Technology)+ 3 AuthorsPhilip C. Bevilacqua42
Estimated H-index: 42
(Pennsylvania State University)
Membraneless compartments, such as complex coacervates, have been hypothesized as plausible prebiotic micro-compartments due to their ability to sequester RNA; however, their compatibility with essential RNA World chemistries is unclear. We show that such compartments can enhance key prebiotically-relevant RNA chemistries. We demonstrate that template-directed RNA polymerization is sensitive to polycation identity, with polydiallyldimethylammonium chloride (PDAC) outperforming poly(allylamine), ...
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Published on Jan 11, 2019in Nature Communications 12.35
Jin Liu13
Estimated H-index: 13
(Stanford University),
Qingyang Hu10
Estimated H-index: 10
+ 7 AuthorsWendy L. Mao34
Estimated H-index: 34
(Stanford University)
A drastically altered chemistry was recently discovered in the Fe-O-H system under deep Earth conditions, involving the formation of iron superoxide (FeO2Hx with x = 0 to 1), but the puzzling crystal chemistry of this system at high pressures is largely unknown. Here we present evidence that despite the high O/Fe ratio in FeO2Hx, iron remains in the ferrous, spin-paired and non-magnetic state at 60–133 GPa, while the presence of hydrogen has minimal effects on the valence of iron. The reduced ir...
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Published on Feb 19, 2019in Nature Communications 12.35
Pierre-Yves Jacob3
Estimated H-index: 3
(Aix-Marseille University),
Fabrizio Capitano (Aix-Marseille University)+ 2 AuthorsFrancesca Sargolini17
Estimated H-index: 17
(Aix-Marseille University)
Entorhinal grid cells are thought to provide a 2D spatial metric of the environment. In this study we demonstrate that in a familiar 1D circular track (i.e., a continuous space) grid cells display a novel 1D equidistant firing pattern based on integrated distance rather than travelled distance or time. In addition, field spacing is increased compared to a 2D open field, probably due to a reduced access to the visual cue in the track. This metrical modification is accompanied by a change in LFP t...
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Published on Mar 12, 2019in Nature Communications 12.35
Samuel C. Kimmey2
Estimated H-index: 2
(Stanford University),
Luciene Borges (Stanford University)+ 1 AuthorsSean C. Bendall29
Estimated H-index: 29
(Stanford University)
Cellular products derived from the activity of DNA, RNA, and protein synthesis collectively control cell identity and function. Yet there is little information on how these three biosynthesis activities are coordinated during transient and sparse cellular processes, such as activation and differentiation. Here, we describe Simultaneous Overview of tri-Molecule Biosynthesis (SOM3B), a molecular labeling and simultaneous detection strategy to quantify DNA, RNA, and protein synthesis in individual ...
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Published on Feb 27, 2019in Nature Communications 12.35
Yiqing Chen4
Estimated H-index: 4
(Fudan University),
Hehua Liu5
Estimated H-index: 5
(Fudan University)
+ 11 AuthorsXuhang Li1
Estimated H-index: 1
(Fudan University)
African swine fever virus (ASFV) is contagious and can cause highly lethal disease in pigs. ASFV DNA ligase (AsfvLIG) is one of the most error-prone ligases identified to date; it catalyzes DNA joining reaction during DNA repair process of ASFV and plays important roles in mutagenesis of the viral genome. Here, we report four AsfvLIG:DNA complex structures and demonstrate that AsfvLIG has a unique N-terminal domain (NTD) that plays critical roles in substrate binding and catalytic complex assemb...
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