Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer’s disease
Abstract
Cerebral amyloid angiopathy (CAA) often coexists with Alzheimer's disease (AD). APOE4 is a strong genetic risk factor for both AD and CAA. Sex-dependent differences have been shown in AD as well as in cerebrovascular diseases. Therefore, we examined the effects of APOE4, sex, and pathological components on CAA in AD subjects. A total of 428 autopsied brain samples from pathologically confirmed AD cases were analyzed. CAA severity was...
Paper Details
Title
Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer’s disease
Published Date
May 14, 2016
Journal
Volume
132
Issue
2
Pages
225 - 234
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