Effect of the volume and intensity of exercise training on insulin sensitivity

Published on Jan 1, 2004in Journal of Applied Physiology3.14
· DOI :10.1152/japplphysiol.00707.2003
Joseph A. Houmard58
Estimated H-index: 58
Charles J. Tanner27
Estimated H-index: 27
+ 3 AuthorsWilliam E. Kraus79
Estimated H-index: 79
Physical activity enhances insulin action in obese/overweight individuals. However, the exercise prescription required for the optimal enhancement is not known. The purpose of this study was to test the hypothesis that exercise training consisting of vigorous-intensity activity would enhance insulin sensitivity more substantially than moderate-intensity activity. Sedentary, overweight/obese subjects (n = 154) were randomly assigned to either control or an exercise group for 6 mo: 1) low-volume/moderate-intensity group [∼12 miles walking/wk at 40–55% peak O2 consumption (Vo2 peak)], 2) low-volume/high-intensity group (∼12 miles jogging/wk at 65–80% Vo2 peak), and 3) high-volume/high-intensity group (∼20 miles jogging/wk at 65–80% Vo2 peak). Training volume (miles/wk) was achieved by exercising ∼115 min/wk (low-volume/high-intensity group) or ∼170 min/wk (low-volume/moderate-intensity and high-volume/high-intensity groups). Insulin action was measured with an insulin sensitivity index (SI) from an intrav...
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