Original paper
Post-mortem assessment of hypoperfusion of cerebral cortex in Alzheimer’s disease and vascular dementia
Abstract
Perfusion is reduced in the cerebral neocortex in Alzheimer’s disease. We have explored some of the mechanisms, by measurement of perfusion-sensitive and disease-related proteins in post-mortem tissue from Alzheimer’s disease, vascular dementia and age-matched control brains. To distinguish physiological from pathological reduction in perfusion (i.e. reduction exceeding the decline in metabolic demand), we measured the concentration of vascular...
Paper Details
Title
Post-mortem assessment of hypoperfusion of cerebral cortex in Alzheimer’s disease and vascular dementia
Published Date
Feb 15, 2015
Journal
Volume
138
Issue
4
Pages
1059 - 1069
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Notes
History