Application of high-dose propofol during ischemia improves postischemic function of rat hearts: effects on tissue antioxidant capacity

Volume: 82, Issue: 10, Pages: 919 - 926
Published: Oct 1, 2004
Abstract
Previous studies have shown that reactive oxygen species mediated lipid peroxidation in patients undergoing cardiac surgery occurs primarily during cardiopulmonary bypass. We examined whether application of a high concentration of propofol during ischemia could effectively enhance postischemic myocardial functional recovery in the setting of global ischemia and reperfusion in an isolated heart preparation. Hearts were subjected to 40 min of...
Paper Details
Title
Application of high-dose propofol during ischemia improves postischemic function of rat hearts: effects on tissue antioxidant capacity
Published Date
Oct 1, 2004
Volume
82
Issue
10
Pages
919 - 926
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