Abnormal Neural Sensitivity to Monetary Gains Versus Losses Among Adolescents at Risk for Depression

Major depressive disorder aggregates within families, although the mechanisms of transfer across generations are not well understood. In light of converging biological and behavioral evidence that depressive symptoms are associated with impaired reward processing, we examined whether adolescent girls with a parental history of depression would also exhibit abnormal reward sensitivity. We performed a negative mood induction and then recorded the...