Time lapse microphotography of protein crystal growth using a color VCR

A time lapse video color recorder (VCR) interfaced to a color video camera mounted on a light microscope was used to observe and record the growth of three protein crystals: lysozyme, canavalin, and a fungal protease. The studies produced a number of interesting observations regarding the formation of crystal habit, crystal aggregates, and crystal polymorphs. It further provided a simple and easy means for the measurement of growth rates. The...