Monkeypox Virus Outbreaks and Poxvirus Infections: Transmission Routes and Epidemiological Characteristics

While the eradication of smallpox virus, which is a success story achieved through a common struggle in human history, eliminated a major threat, the most important advantage was that the agent (variola virus) was not of zoonotic origin. The absence of smallpox infections around the world and the termination of extensive vaccination programs have led to a decrease in global orthopoxvirus immunity day by day. The increasing number of non-immune...