Original paper
PLS3 Mutations Cause Severe Age and Sex-Related Spinal Pathology
Abstract
Objective: Mutations in the X-chromosomal PLS3-gene, encoding Plastin 3, lead to severe early-onset osteoporosis, suggesting a major role for PLS3 in bone metabolism. However, the consequences of abnormal PLS3 function in bone and other tissues remain incompletely characterized. This study evaluated spinal consequences of aberrant PLS3 function in patients with PLS3 mutations. Design: A cross-sectional cohort study with spinal magnetic resonance...
Paper Details
Title
PLS3 Mutations Cause Severe Age and Sex-Related Spinal Pathology
Published Date
Jun 23, 2020
Journal
Volume
11
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Notes
History