Protective mechanisms of hydrogen sulfide in myocardial ischemia

Hydrogen sulfide (H 2 S), which has been identified as the third gaseous signaling molecule after nitric oxide (NO) and carbon monoxide (CO), plays an important role in maintaining homeostasis in the cardiovascular system. Endogenous H 2 S is produced mainly by three endogenous enzymes: cystathionine β‐synthase, cystathionine γ‐lyase, and 3‐mercaptopyruvate sulfur transferase. Numerous studies have shown that H 2 S has a significant protective...